HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate → HCID 46195319, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate | HCID 66726782 | — |
| Reactant | HCID 131733965 | HCID 131733965 | — |
| Product | HCID 46195319 | HCID 46195319 | 78% |
Reaction Steps
When the product of Step C was substituted for tert-butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 34, Step E, the identical process afforded the title compound in 78% yield. 1H-NMR (DMSO-d6) 1.75 (s, 6H); 2.07 (s, 9H); 2.97-3.57 (m, 12H); 6.7 (d, 1H, J=7.6 Hz); 7.12 (tr, 1H); 7.34 (d, 1H, J=7.7 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181182B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-929fb778ebb14d6098068b2c72639aaf |
| Source note | uspto-grants-2015_11 |