tert-Butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate → HCID 46195322, compound

Participants

Reaction Steps

When the product of Step E was substituted for tert-butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 34, Step E, the identical process afforded the title compound in 100%. 1H-NMR (CD3OD/CDCl3) 2.8-2.86 (m, 4H); 2.89 (tr, 2H, J=8.29 Hz); 3.0 (s, 2H); 3.39 (tr, 2H, J=8.29 Hz); 3.48 (d, 2H, J=10.88 Hz); 3.55 (d, 2H, J=10.92 Hz); 6.51 (d, 1H, J=8.6 Hz); 6.86-6.88 (m, 2H); 7.14 (m, 3H); 7.17-7.37 (m, 2H); 7.4 (tr, 1H, J=7.57 Hz); 7.5 (tr, 1H, J=7.01 Hz); 7.68 (d, 1H, J=7.77 Hz).

Provenance & Evidence