tert-Butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate → HCID 46195463, compound

Participants

Reaction Steps

When the product of Step G was substituted for tert-butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 34, Step E, the identical process afforded the title compound in 49% yield. 1H-NMR (CDCl3) 1.34 (d, 6H, J=6.00 Hz); 1.73 (s, 6H); 2.03 (s, 3H); 2.08 (s, 6H); 2.4 (s, 3H); 2.51 (s, 2H); 2.66 (s, 4H); 3.42 (d, 2H, J=10.87 Hz); 3.47 (d, 2H, J=10.88 Hz); 4.56-4.61 (m, 1H); 6.72 (d, 1H, J=8.34 Hz); 6.98 (dd, 1H, J=2.12, 8.24 Hz); 6.97 (d, 1H, J=2.12 Hz).

Provenance & Evidence