HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(1-Admantyl)-4-hydroxybenzaldehyde → Methyl 4-(1-admantyl)-3-isopropoxybenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(1-Admantyl)-4-hydroxybenzaldehyde | HCID 3407892 | — |
| Reactant | Methyl 3-hydroxy-4-(1-adamantyl)benzoate | HCID 19387991 | — |
| Product | Methyl 4-(1-admantyl)-3-isopropoxybenzoate | HCID 66729638 | 75.4% |
Reaction Steps
When methyl 4-(1-admantyl)-3-hydroxybenzoate was substituted for 3-(1-admantyl)-4-hydroxybenzaldehyde in Example 60, Step A, the identical process afforded the title compound (0.95 g, 75.4%) as a colourless solid. 1H-NMR (CDCl3) 1.39 (d, 6H, J=6 Hz); 1.75 (5, 6H); 2.05 (s, 3H); 2.11 (s, 6H); 3.87 (s, 3H); 4.69-4.71 (m, 1H); 7.24 (d, 1H, J=8.1 Hz); 7.47 (b, 1H); 7.51 (dd, 1H, J=1.55, 8.09 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181182B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-bc24a65393ea4ad7b135cd17e0e86884 |
| Source note | uspto-grants-2015_11 |