HRID710467

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2782313

5-Iodoindole

C8H6IN

HCID57753580

tert-Butyl 5-iodo-1,3-dihydro-2H-isoindole-2-carboxylate

C13H16INO2

PRODUCTS

生成物

HCID18630967

tert-Butyl 5-cyano-1,3-dihydro-2H-isoindole-2-carboxylate

C14H16N2O2

PROCEDURE

实验过程

When the product of Step B was substituted for 5-iodoindole in Example 7, Step A, the similar process afforded the title compound in 85%, as colourless solid, after purification by FCC (SiO2; CH2Cl2). 1H-NMR (CDCl3) 1.49 (s, 9H); 4.56-4.72 (m, 4H); 7.32-7.37 (m, 1H); 7.49-7.56 (m, 2H).