HCID 86661813, compound → HCID 46195747, compound

Participants

Reaction Steps

When the product of Step D was substituted for tea-butyl 2,2-dimethyl-5-((4-(5-(6-propylpyridin-3-yl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-1,3-dioxan-5-ylcarbamate in Example 66, Step F, the identical process afforded the title compound in 45% yield, as colourless solid. 1H-NMR (CDCl3+CD3OD) 0.92 (tr, 3H, J=6 Hz); 1.56-1.67 (m, 2H+H2O); 2.55-2.65 (m, 2H); 2.91 (tr, 2H, J=(Hz); 2.98 (s, 2H); 3.39 (tr, 2H, J=6 Hz); 3.4-3.6 (m, 4H); 5.02 (s, 2H); 6.5 (d, 1H, J=9 Hz); 6.64 (s, 1H); 6.68-6.81 (m, 2H); 7.06 (dd, 1H, J=3, 9 Hz); 7.28-7.37 (m, 2H).

Provenance & Evidence