3,4-Difluorobenzylamine → HCID 178505785, compound

Participants

Reaction Steps

The compound was synthesized starting from 5-(1,3,4-oxadiazol-2-yl)benzimidazole (186 mg, 1 mmol) and 3,4-difluorobenzylamine (0.5 ml) as described above; yield: 0.049 g (15.8%); MS m/z: 312.2 [M+H]+; 1H-NMR (DMSO d6, 400 MHz): δ 5.36 (s, 2H); 6.81-6.84 (m, 1H); 7.13-7.19 (m, 1H); 7.29-7.36 (m, 1H); 7.59 (dd, 1H, 4J=1.7 Hz, 3J=8.7 Hz); 7.82 (d, 1H, 3J=8.7 Hz); 7.88 (d, 1H, 4J=1.7 Hz); 8.77 (s, 1H); 9.03 (s, 1H); HPLC (METHOD [A]): it 8.82 min (95.6%)

Provenance & Evidence