3,4,5-Trimethoxyhydrocinnamic acid → HCID 178489912, compound

Participants

Reaction Steps

The compound was synthesized starting from benzimidazol-5-carbohydrazide (176 mg, 1 mmol) and 3-(3,4,5-trimethoxyphenyl)propionic acid (241 mg; 1 mmol) as described in method 2; yield: 0.016 g (4.2%); MS m/z: 381.4 [M+H]+; 1H-NMR (CD3OD, 400 MHz): δ 3.12-3.16 (m, 2H); 3.31-3.33 (m, 2H); 3.70 (s, 3H), 3.77 (s, 6H); 6.56 (s, 2H); 7.94 (d, 1H, 3J=8.7 Hz); 8.15 (dd, 1H, 4J=1.7 Hz, 3J=8.7 Hz); 8.381-8.382 (m, 1H); 9.12 (s, 1H); HPLC (METHOD [A]): rt 10.41 min (89.6%)

Provenance & Evidence