3-(2,4-difluorophenyl)propanoic Acid → HCID 178505668, compound

HRID 710517Notes

Reaction equation

HRID 710517 reaction equation
[N:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([NH:12][NH2:13])=[O:11])=[CH:9][C:4]=2[NH:3][CH:2]=1.[F:14][C:15]1[CH:20]=[C:19]([F:21])[CH:18]=[CH:17][C:16]=1[CH2:22][CH2:23][C:24](O)=O>>[F:14][C:15]1[CH:20]=[C:19]([F:21])[CH:18]=[CH:17][C:16]=1[CH2:22][CH2:23][C:24]1[O:11][C:10]([C:8]2[CH:7]=[CH:6][C:5]3[NH:1][CH:2]=[N:3][C:4]=3[CH:9]=2)=[N:12][N:13]=1

Participants

3

Reactant 2

HCID 49863953-(2,4-difluorophenyl)propanoic AcidHCID 166371191H-benzimidazole-5-carbohydrazide

Product 1

HCID 178505668HCID 178505668, compound

Procedure

The compound was synthesized starting from benzimidazol-5-carbohydrazide (176 mg, 1 mmol) and 3-(2,4-difluorophenyl)propionic acid (186 mg, 1 mmol) as described in method 2;

Workup

  1. customThe compound was synthesized

Sources & evidence

ORD record
ord-933494eae8fe4639aef2c4123e871cd1
Source dataset
uspto-grants-2015_11
Patent number
US09181233B2

Reaction notes

Loading…