3-(3-chloro-4-methoxyphenyl)propanoic acid → HCID 178490022, compound

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Reaction Steps

The compound was synthesized starting from benzimidazol-5-carbohydrazide (176 mg, 1 mmol) and 3-(3-chloro-4-methoxyphenyl)propionic acid (215 mg; 1 mmol) as described in method 2; yield: 0.071 g (20.1%); MS m/z: 355.4/357.1 [M+H]+; 1H-NMR (DMSO d6, 400 MHz): δ 3.06-3.08 (m, 2H); 3.24-3.27 (m, 2H); 3.80 (s, 3H); 7.04-7.06 (m, 1H); 7.21-7.23 (m, 1H); 7.39 (br s, 1H); 7.87-7.89 (m, 1H); 7.94-7.96 (m, 1H); 8.25 (br s, 1H); 8.92 (s, 1H); HPLC (METHOD [A]): rt 12.55 min (95.7%)

Provenance & Evidence