Phenoxyacetic Acid → HCID 178420516, compound

Participants

Reaction Steps

The compound was synthesized starting from Benzimidazol-5-carbohydrazide (176 mg, 1 mmol) and Phenoxyacetic acid (153 mg; 1 mmol) as described in method 2 but purified by flash chromatography on silica using a CHCl3/MeOH gradient; yield: 0.049 g (16.8%); MS m/z: 293.2 [M+H]+; 1H-NMR (DMSO d6, 400 MHz): □5.48 (s, 2H); 7.00-7.03 (m, 1H); 7.11-7.13 (m, 2H); 7.32-7.36 (m, 2H); 7.78 (d, 1H, 3J=8.3 Hz); 7.86 (dd, 1H, 4J=1.7 Hz, 3J=8.3 Hz); 8.20 (br s, 1H); 8.40 (s, 1H); 12.82 (br s, 1H); HPLC (METHOD [A]): rt 11.29 min (100%)

Provenance & Evidence