Dicyclohexylcarbodiimide → HCID 178489913, compound

Participants

Reaction Steps

The compound was synthesized starting from 3-(3,4,5-trimethoxyphenyl)propionic acid (241 mg; 1 mmol), DCC (206 mg; 1 mmol), benzimidazol-5-carbohydrazide (176 mg; 1 mmol) and Lawesson's reagent (606 mg; 1.5 mmol) as described in method 2; yield: 0.033 g (8.3%); MS m/z: 397.3 [M+H]+; 1H-NMR (DMSO d6, 400 MHz): δ 3.04 (t, 2H, 3J=7.9 Hz); 3.47 (t, 2H, 3J=7.9 Hz); 3.62 (s, 3H); 3.74 (s, 6H); 6.62 (s, 2H); 7.83 (d, 1H, 3J=8.7 Hz); 7.93 (dd, 1H, 4J=1.7 Hz, 3J=8.7 Hz); 8.22 (d, 1H, 4J=1.7 Hz); 8.91 (s, 1H); HPLC (METHOD [A]): rt 11.54 min (98.2%)

Provenance & Evidence