Dicyclohexylcarbodiimide → HCID 178490063, compound

Participants

Reaction Steps

The compound was synthesized starting from 3-(3-methoxyphenyl)propionic acid (181 mg; 1 mmol), DCC (206 mg; 1 mmol), benzimidazol-5-carbohydrazide (176 mg; 1 mmol) and Lawesson's reagent (606 mg; 1.5 mmol) as described in method 2; yield: 0.019 g (5.7%); MS m/z: 337.3 [M+H]+; 1H-NMR (DMSO d6, 400 MHz): δ 3.08 (t, 2H, 3J=7.5 Hz); 3.46 (t, 2H, 3J=7.5 Hz); 3.72 (s, 3H); 6.76-6.78 (m, 1H); 6.85-6.88 (m, 2H); 7.20 (t, 1H, 3J=7.9 Hz); 7.81 (d, 1H, 3J=8.7 Hz); 7.89 (dd, 1H, 4J=1.7 Hz, 3J=8.7 Hz); 8.20 (d, 1H, 4J=1.7 Hz); 8.83 (s, 1H); HPLC (METHOD [A]): rt 12.24 min (95.9%)

Provenance & Evidence