Dicyclohexylcarbodiimide → HCID 178490064, compound

Participants

Reaction Steps

The compound was synthesized starting from 3-(2-Chlor-3-methoxyphenyl)propionic acid (215 mg; 1 mmol), DCC (206 mg; 1 mmol), Benzimidazol-5-carbohydrazide (176 mg; 1 mmol) and Lawesson's reagent (606 mg; 1.5 mmol) as described in method 2; yield: 0.015 g (4.1%); MS m/z: 371.3 [M+H]+; 1H-NMR (DMSO d6, 400 MHz): δ 3.20-3.24 (m, 2H); 3.42-3.46 (m, 2H); 3.84 (s, 3H); 6.98-7.04 (m, 2H); 7.22-7.26 (m, 1H); 7.78-7.80 (m, 1H); 7.86-7.89 (m, 1H); 8.20 (br s, 1H); 8.72 (s, 1H); HPLC (METHOD [A]): rt 13.13 min (97.8%)

Provenance & Evidence