Phosphorus oxychloride → HCID 178527396, compound

Participants

Reaction Steps

The compound was synthesized starting from phenylsulfonylacetic acid (201 mg; 1 mmol), benzimidazol-5-carbohydrazide (176 mg; 1 mmol), Lawesson's reagent (606 mg; 1.5 mmol) and POCl3 (0.137 ml; 1.5 mmol) as described in method 3; yield: 0.051 G (14.3%); MS m/z: 357.1 [M+H]+; 1H-NMR (DMSO d6, 400 MHz): δ 5.51 (s, 2H); 7.63-7.67 (m, 2H); 7.75-7.77 (m, 1H); 7.84-7.87 (m, 3H); 7.98 (dd, 1H, 4J=1.7 Hz, 3J=8.3 Hz); 8.30 (d, 1H, 4J=1.7 Hz); 8.95 (s, 1H); HPLC (METHOD [A]): rt 10.49 min (98.3%)

Provenance & Evidence