HCID 68266097, compound → HCID 68266098, compound

Participants

Reaction Steps

A solution of N-(3,5-Difluoro-4-(4-methoxybenzylamino)pyridin-2-yl)propane-1-sulfonamide (1.05 g) in DCM (50 ml) and TFA (20 ml) was stirred at rt for 16 h. The mixture was concentrated. The residue was taken up in aqueous sodium bicarbonate solution, and the mixture was extracted with DCM. The combined organic extracts were dried over sodium sulfate, filtered, and concentrated. The residue was chromatographed on silica gel (10-50% ethyl acetate in hexanes eluant) to provide the title compound. MS m/z: 251.9 (M+1).

Provenance & Evidence