HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Benzeneethanamine, 4-chloro-N-(2-chloropropyl)-, hydrochloride (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 1-((4-Chlorophenethyl)amino)propan-2-ol | HCID 11564750 | — |
| Product | Benzeneethanamine, 4-chloro-N-(2-chloropropyl)-, hydrochloride (1:1) | HCID 44222956 | — |
Reaction Steps
In some embodiments, after reacting 1-(4-chlorophenethylamino)propan-2-ol with thionyl chloride, produces 2-chloro-N-(4-chlorophenethyl)propan-1-amine hydrochloride with a purity of about 95% or greater as determined by HPLC. In some embodiments, after reacting 1-(4-chlorophenethylamino)propan-2-ol with thionyl chloride, the 2-chloro-N-(4-chlorophenethyl)propan-1-amine hydrochloride with a purity of about 98% or greater as determined by HPLC. In some embodiments, “HPLC” refers to Reversed-Phase High Performance Liquid Chromatography. In some embodiments, “HPLC” refers to Normal-Phase High Performance Liquid Chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822727B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-75a4634ab12f4e5e94128d63d8b7edb5 |
| Source note | uspto-grants-2014_09 |