HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-3-((1RS,2SR,4SR)-2-methyl-3-methylenebicyclo[2.2.1]hept-5-en-2-yl)acrylaldehyde → HCID 15599971, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-3-((1RS,2SR,4SR)-2-methyl-3-methylenebicyclo[2.2.1]hept-5-en-2-yl)acrylaldehyde | HCID 89904621 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Water ethanol | HCID 19096565 | — |
| Product | HCID 15599971 | HCID 15599971 | 85% |
Reaction Steps
Obtained in 85% yield by hydrogenation of 23 (2.0-mol-equiv. of H2) over Raney-Ni (5% by weight) at 0° in EtOH/H2O 95:5. (90% based on the recovered SM). For analyses, see H. Sonawane, R. Harikisan, N. S. Bellur, J. R. Ahuja, D. J. Kulkarni, J. Org. Chem. 1991, 56, 1434; M. Saito, M. Kawamura, K. Ogasawara, Tetr. Lett. 1995, 36, 9003; D. Solas, J. Wolinsky, J. Org. Chem. 1983, 48, 1988; P. A. Christenson, B. J. Willis, J. Org. Chem. 1979, 44, 2012.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822733B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-d33f4b207d6742c5a72fcb4c21caafaf |
| Source note | uspto-grants-2014_09 |