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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 710785Generated: October 30, 2026

2-Methyl-5-vinylpyridine → HCID 57875955, compound

https://huagongshe.com/reaction/710785

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-5-vinylpyridineHCID 8817—
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 68927579HCID 68927579—
SolventN-methyl-2-pyrrolidoneHCID 13387—
ProductHCID 57875955HCID 57875955—

Reaction Steps

The title compound is prepared from a mixture of 3,4-dihydro-2-(hydroxymethyl)-8-methyl-2H-pyrido[4,3-b]indol-1(5H)-one, 2-methyl-5-vinylpyridine and KOH (5-7 equiv) in NMP at a temperature ranging between 25 deg C. to 100 deg C. The product obtained is isolated by preparative HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181240B2
Source datasetuspto-grants-2015_11
ORD IDord-38b5d20bb5764081aec7451fa4e3f094
Source noteuspto-grants-2015_11