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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 710869Generated: October 30, 2026

Potassium Hydroxide → HCID 57876150, compound

https://huagongshe.com/reaction/710869

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
Reactant8-chloro-2-methyl-1H,2H,3H,4H,5H-pyrido(4,3-b)indoleHCID 19615—
Reactant3-ethenylquinolineHCID 11435064—
SolventN-methyl-2-pyrrolidoneHCID 13387—
ProductHCID 57876150HCID 57876150—

Reaction Steps

The title compound is prepared from a mixture of 8-chloro-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indole, 3-vinylquinoline and KOH (5-7 equiv) in NMP at a temperature ranging between 25 deg C. to 100 deg C. The product obtained is isolated by preparative HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181240B2
Source datasetuspto-grants-2015_11
ORD IDord-c6f06846b21e4b5497308c1bfc3c8f3e
Source noteuspto-grants-2015_11