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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 710882Generated: October 29, 2026

Potassium Hydroxide → HCID 57876172, compound

https://huagongshe.com/reaction/710882

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
Reactant1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2,8-dimethyl-HCID 209291—
ReactantN-(5-Ethenyl-3-methylpyridin-2-yl)acetamideHCID 57416850—
SolventN-methyl-2-pyrrolidoneHCID 13387—
ProductHCID 57876172HCID 57876172—

Reaction Steps

The title compound is prepared from a mixture of 2,3,4,5-tetrahydro-2,8-dimethyl-1H-pyrido[4,3-b]indole, N-(3-methyl-5-vinylpyridin-2-yl)acetamide and KOH (5-7 equiv) in NMP at a temperature ranging between 25 deg C. to 100 deg C. The product obtained is isolated by preparative HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181240B2
Source datasetuspto-grants-2015_11
ORD IDord-76e357083ab446bc92f224ed8fa2821b
Source noteuspto-grants-2015_11