1-Methyl-4-piperidone → HCID 57876051, compound

HRID 710894Notes

Reaction equation

HRID 710894 reaction equation
Br[CH2:2][C:3]1([C:6]2[CH:7]=[CH:8][C:9]([CH3:12])=[N:10][CH:11]=2)[CH2:5][CH2:4]1.C(N(CC)CC)C.Cl.[CH3:21][C:22]1[CH:27]=[CH:26][C:25]([NH:28]N)=[CH:24][CH:23]=1.[CH3:30][N:31]1[CH2:36][CH2:35][C:34](=O)[CH2:33][CH2:32]1>>[CH3:30][N:31]1[CH2:36][CH2:35][C:34]2[N:28]([CH2:2][C:3]3([C:6]4[CH:11]=[N:10][C:9]([CH3:12])=[CH:8][CH:7]=4)[CH2:5][CH2:4]3)[C:25]3[CH:24]=[CH:23][C:22]([CH3:21])=[CH:27][C:26]=3[C:33]=2[CH2:32]1

Participants

4

Reactant 3

HCID 740491-Methyl-4-piperidoneHCID 68923274HCID 68923274, compoundHCID 86685442HCID 86685442, compound

Product 1

HCID 57876051HCID 57876051, compound

Procedure

The title compound is prepared by following Method 8 by using 5-(1-(bromomethyl)cyclopropyl)-2-methylpyridine, (4-methylphen ylhydrazine hydrochloride triethylamine and N-methyl-4-piperidone.

Sources & evidence

ORD record
ord-93d5e2b123dd459298bbf2dae5041b54
Source dataset
uspto-grants-2015_11
Patent number
US09181240B2

Reaction notes

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