HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Oxazole-4-carbohydrazide → HCID 117988378, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Oxazole-4-carbohydrazide | HCID 49761715 | — |
| Reactant | (2S,5R)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid | HCID 57389355 | — |
| Product | HCID 117988378 | HCID 117988378 | 61.7% |
Reaction Steps
Following a procedure analogous to Example 27, from the carboxylic acid (6b, 390 mg, 1.41 mmol) of Example 9 or 16 and oxazol-4-carbohydrazide (613 mg, prepared following a procedure analogous to Reference Example 2), 335.2 mg of the title compound was afforded (yield 61.7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181250B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-10a4c68ba69c44e0986757eb9c22330b |
| Source note | uspto-grants-2015_11 |