HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dimethylethyl (2R)-2-[(aminooxy)methyl]-1-pyrrolidinecarboxylate → HCID 72549640, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dimethylethyl (2R)-2-[(aminooxy)methyl]-1-pyrrolidinecarboxylate | HCID 11413283 | — |
| Reactant | (2S,5R)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid | HCID 57389355 | — |
| Product | HCID 72549640 | HCID 72549640 | 50.2% |
Reaction Steps
Following a procedure analogous to Example 27, from the carboxylic acid (6b, 390 mg, 1.41 mmol) of Example 9 or 16 and (R)-tert-butyl 2-((aminooxy)methyl)pyrrolidine-1-carboxylate (796 mg) described in Reference Example 22, 336 mg of the title compound was afforded (yield 50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181250B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-532dfecf3a544897a3075691abb66b00 |
| Source note | uspto-grants-2015_11 |