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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 710997Generated: October 29, 2026

HCID 39247806, compound → HCID 72549639, compound

https://huagongshe.com/reaction/710997

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 39247806HCID 39247806—
Reactant(2S,5R)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acidHCID 57389355—
ProductHCID 72549639HCID 7254963972.3%

Reaction Steps

Following a procedure analogous to Example 45, from the carboxylic acid (6b, 276 mg, 1.00 mmol) of Example 9 or 16 and (S)-tert-butyl 2-((aminooxy)methyl)piperidine-1-carboxylate (300 mg) described in Reference Example 23, 353.3 mg of the title compound was afforded (yield 72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181250B2
Source datasetuspto-grants-2015_11
ORD IDord-befd15f5714040f3b58327691f16637f
Source noteuspto-grants-2015_11