反应详情

Ferulic acid (2.0 gms) was dissolved in ethanol (10 ml) and sitagliptin free base (1.9 gms) was added to the clear solution and stirred for 15 min. Additional ethanol (10 ml) was added to the semi precipitated reaction mass and stirring was continued for 48 hours at room temperature. Precipitated solids were filtered off and dried at 70° C. to 75° C. for 24 hours to obtain the title compound. Yield: 1.37 gms.

1. customprecipitated
2. customreaction mass
3. stirringstirring
4. waitwas continued for 48 hours at room temperature
5. customPrecipitated solids
6. filtrationwere filtered off
7. customdried at 70° C. to 75° C. for 24 hours