HCID 54787870, compound → HCID 178516422, compound

Participants

Reaction Steps

To the heated Dowtherm A (200 mL) at 200° C. was added 5-((6-chloropyridin-3-ylamino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione (3.5 g, 12.4 mmol) and then stirred for additional 5 min. After cooling to r.t., PE was added. The precipitate was collected, and dried in vacuo to afford 6-chloro-1,5-naphthyridin-4-ol as off-white solid in 42% yield (0.94 g). m/z 183 (M+H)+

Provenance & Evidence