Hydrazine hydrate (1:1) → 7-Bromo-2-hydrazinylquinoxaline

Participants

Reaction Conditions

Reaction Steps

To the solution of 7-bromo-2-chloroquinoxaline (2 g, 8.2 mmol) in ethanol (20 mL) was added hydrazine hydrate (85%, 4.5 mL, 32.8 mmol). The mixture was heated to 78° C. for 2 h. After cooling to r.t., the precipitate was collected by filtration to afford 7-bromo-2-hydrazinylquinoxaline as white solid in 87% yield (1.7 g).

Provenance & Evidence