HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-Methoxy-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | N-(3-cyano-4,5-dimethylthiophen-2-ylcarbamoyl)benzamide | HCID 57456902 | — |
| Product | 2-Methoxy-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine | HCID 25224339 | 86% |
Reaction Steps
Prepared in a similar manner to Example 25 from N-(3-cyano-4,5-dimethylthiophen-2-ylcarbamoyl)benzamide (Example 4a) and methyl iodide in 86% yield. 1H NMR (400 MHz, CDCl3) δ 2.35 (s, 3H), 2.36 (s, 3H), 3.53 (s, 3H), 6.0 (bs, 2H). MS 210 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181276B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-a5652d55af4f47158938fcd5bd46bd46 |
| Source note | uspto-grants-2015_11 |