HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Methylhydroxylamine → 2-(Methoxyamino)quinazolin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Methylhydroxylamine | HCID 4113 | — |
| Reactant | 2-Chloroquinazolin-4-amine | HCID 252879 | — |
| Product | 2-(Methoxyamino)quinazolin-4-amine | HCID 57456921 | — |
Reaction Steps
Prepared as in Example 42 from 2-chloroquinazolin-4-amine (Example 38) and methoxylamine. 1H NMR (400 MHz, DMSO-d6) δ 3.79 (s, 3H), 7.48-7.44 (m, 1H), 7.86-7.80 (m, 2H), 8.27 (d, J=8.0 Hz, 1H), 8.99 (s, 1H), 9.16 (s, 1H), 12.39-12.08 (m, 1H). MS 191 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181276B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-99e43e68a5c8421eb3d4b63b5638a6e2 |
| Source note | uspto-grants-2015_11 |