Propyl isocyanate → HCID 66745855, compound

HRID 711780Notes

Reaction equation

HRID 711780 reaction equation
[Cl-].[C:2]([C:4]1[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][CH:14]=[CH:13][C:5]=1[O:6][CH2:7][C@H:8]1[CH2:12][CH2:11][CH2:10][NH2+:9]1)#[N:3].[CH2:20]([N:23]=[C:24]=[O:25])[CH2:21][CH3:22]>>[C:2]([C:4]1[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][CH:14]=[CH:13][C:5]=1[O:6][CH2:7][C@H:8]1[CH2:12][CH2:11][CH2:10][N:9]1[C:24]([NH:23][CH2:20][CH2:21][CH3:22])=[O:25])#[N:3]

Participants

3

Reactant 2

HCID 61033Propyl isocyanateHCID 66746622HCID 66746622, compound

Product 1

HCID 66745855HCID 66745855, compoundYield 100%

Procedure

Prepared as in Example 176b from (R)-2-((2-cyano-3-nitrophenoxy)methyl)pyrrolidinium chloride (Example 176c) and propyl isocyanate in 100% yield as a light yellow solid. MS 333 (MH+).

Sources & evidence

ORD record
ord-e5157dfc42464729b79e50f12287e1fa
Source dataset
uspto-grants-2015_11
Patent number
US09181276B2

Reaction notes

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