Ethyl isocyanate → HCID 66746551, compound

HRID 711781Notes

Reaction equation

HRID 711781 reaction equation
[Cl-].[C:2]([C:4]1[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][CH:14]=[CH:13][C:5]=1[O:6][CH2:7][C@H:8]1[CH2:12][CH2:11][CH2:10][NH2+:9]1)#[N:3].[CH2:20]([N:22]=[C:23]=[O:24])[CH3:21]>>[C:2]([C:4]1[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][CH:14]=[CH:13][C:5]=1[O:6][CH2:7][C@H:8]1[CH2:12][CH2:11][CH2:10][N:9]1[C:23]([NH:22][CH2:20][CH3:21])=[O:24])#[N:3]

Participants

3

Reactant 2

HCID 8022Ethyl isocyanateHCID 66746622HCID 66746622, compound

Product 1

HCID 66746551HCID 66746551, compoundYield 95%

Procedure

Prepared as in Example 176b from (R)-2-((2-cyano-3-nitrophenoxy)methyl)pyrrolidinium chloride (Example 176c) and ethyl isocyanate in 95% yield as a light yellow solid. MS 319 (MH+).

Sources & evidence

ORD record
ord-19f308e123214943a5eeabc5bf473f7f
Source dataset
uspto-grants-2015_11
Patent number
US09181276B2

Reaction notes

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