HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 3-(2-Cyano-3-nitrophenoxy)-2-methylpropyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 2-(3-Hydroxy-2-methylpropoxy)-6-nitrobenzonitrile | HCID 67398858 | — |
| Product | 3-(2-Cyano-3-nitrophenoxy)-2-methylpropyl acetate | HCID 67400532 | 41% |
Reaction Steps
Prepared as in Example 231c from 2-(3-hydroxy-2-methylpropoxy)-6-nitrobenzonitrile (Example 237d) and acetyl chloride in 41% yield. 1H NMR (400 MHz, DMSO-d6) δ 1.04 (d, J=6.8 Hz, 3H), 2.00 (s, 3H), 2.28-2.33 (m, 1H), 4.05-4.08 (m, 2H), 4.18 (d, J=6.0 Hz, 2H), 7.71-7.73 (m, 1H), 7.86-7.92 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181276B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-39ed75c20e9a4799b2e20f289049998f |
| Source note | uspto-grants-2015_11 |