Chlorosulfamic acid → HCID 67400518, compound

HRID 711873Notes

Reaction equation

HRID 711873 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][O:16][Si](C(C)(C)C)(C)C)[C:3]=1[C:4]#[N:5].[S:24](Cl)(=[O:27])(=[O:26])[NH2:25]>>[S:24]([NH:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][OH:16])[C:3]=1[C:4]#[N:5])(=[O:27])(=[O:26])[NH2:25]

Participants

3

Reactant 2

HCID 24499Chlorosulfamic acidHCID 66746845HCID 66746845, compound

Product 1

HCID 67400518HCID 67400518, compoundYield 4%

Procedure

Prepared as in Example 215a from 2-amino-6-(5-(tert-butyldimethylsilyloxy)pentyloxy)benzonitrile (Example 241b) and sulfamoyl chloride in 4% yield. MS 300 (MH+).

Sources & evidence

ORD record
ord-49867aea9472440ba5f86db7ab2bb68d
Source dataset
uspto-grants-2015_11
Patent number
US09181276B2

Reaction notes

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