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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 711891Generated: November 1, 2026

2-Nitro-6-(2-(2-oxopyrrolidin-1-yl)ethoxy)benzonitrile → 2-Amino-6-(2-(2-oxopyrrolidin-1-yl)ethoxy)benzonitrile

https://huagongshe.com/reaction/711891

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Nitro-6-(2-(2-oxopyrrolidin-1-yl)ethoxy)benzonitrileHCID 66746733—
SolventHCID 131731144HCID 131731144—
Product2-Amino-6-(2-(2-oxopyrrolidin-1-yl)ethoxy)benzonitrileHCID 66746322100%

Reaction Steps

Prepared as in example 254b from 2-nitro-6-(2-(2-oxopyrrolidin-1-yl)ethoxy)benzonitrile (Example 257c) using trifluoroethanol/hexafluoroisopropanol (1:1) as solvent in 100% yield MS 246 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181276B2
Source datasetuspto-grants-2015_11
ORD IDord-853785370af9455a9419637d8f38e254
Source noteuspto-grants-2015_11