HCID 12715772, compound → 2-Amino-6-(ethylamino)benzonitrile

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Reaction Steps

Prepared as in Example 254b from 2-(ethylamino)-6-nitrobenzonitrile (Example 259c) using Trifluoroethanol/Hexafluoroisopropanol (2:1) as solvent, in 81% yield. 1H NMR (400 MHz, DMSO-d6) δ 1.14 (t, J=7.2 Hz, 3H), 3.15-3.22 (m, 2H), 5.41 (bt, J=5.2 Hz, NH), 5.64 (s, NH2), 5.82 (d, J=8.0 Hz, 1H), 5.96 (d, J=8.0 Hz, 1H), 7.00 (t, J=8.4 Hz, 1H). MS 162 (MH+).

Provenance & Evidence