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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 711899Generated: October 31, 2026

tert-Butyl Formate → Tert-butyl 3-((2-cyano-3-nitrophenoxy)methyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/711899

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl FormateHCID 61207—
ReactantDinitrobenzonitrileHCID 520718—
Reactanttert-Butyl 3-(hydroxymethyl)piperidine-1-carboxylateHCID 2763851—
ProductTert-butyl 3-((2-cyano-3-nitrophenoxy)methyl)piperidine-1-carboxylateHCID 6674604658%

Reaction Steps

Prepared as in Example 215c from tert-butyl 3-(hydroxymethyl)piperidine-1-carboxylate and 2,6-dinitrobenzonitrile in 58% yield. MS 263 [M+H-Boc]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181276B2
Source datasetuspto-grants-2015_11
ORD IDord-ebe4a0e410d74f2c948e9901e8040485
Source noteuspto-grants-2015_11