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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 711987Generated: October 29, 2026

HCID 178486296, compound → HCID 178486295, compound

https://huagongshe.com/reaction/711987

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178486296HCID 178486296—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 178486295HCID 17848629599.2%

Reaction Steps

A mixture of N-methyl-1-{trans-4-[(6-nitrothieno[3,2-b]pyridin-7-yl)amino]cyclohexyl}methanesulfonamide (35 mg, 0.091 mmol) and 10% palladium on carbon (10 mg) in methanol (1.0 mL) was stirred under an atmosphere of H2 for 10 h. The mixture was filtered through Celite. The filtrate was concentrated under reduced pressure to give the desired product (32 mg). LCMS calculated for C15H23N4O2S2 (M+H)+: m/z=355.1. Found: 355.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181271B2
Source datasetuspto-grants-2015_11
ORD IDord-cf95487acdfb4f869838cb1a0db42d65
Source noteuspto-grants-2015_11