HCID 86717452, compound → HCID 86717453, compound

Participants

Reaction Steps

A mixture of tert-butyl 4-[(6-nitrothieno[3,2-b]pyridin-7-yl)amino]piperidine-1-carboxylate (0.70 g, 1.8 mmol) and 10% palladium on carbon (0.2 g) in methanol (20 mL) was subjected to balloon pressure of H2 at room temperature for 5 h. The reaction mixture was filtered and concentrated and to give the desired product (0.64 g, 100%). LCMS calculated for C17H25N4O2S (M+H)+: m/z=349.2. Found: 349.1.

Provenance & Evidence