Propane → HCID 86717524, compound

HRID 712065Notes

Reaction equation

HRID 712065 reaction equation
[NH2:1][C:2]1[C:3]([NH:11][C@H:12]2[CH2:17][CH2:16][C@H:15]([CH2:18][C:19]#[N:20])[C@@H:14]([O:21][CH3:22])[CH2:13]2)=[C:4]2[S:10][CH:9]=[CH:8][C:5]2=[N:6][CH:7]=1.[CH3:23][CH2:24][CH3:25]>>[CH2:24]([C:25]1[N:11]([C@H:12]2[CH2:17][CH2:16][C@H:15]([CH2:18][C:19]#[N:20])[C@@H:14]([O:21][CH3:22])[CH2:13]2)[C:3]2=[C:4]3[S:10][CH:9]=[CH:8][C:5]3=[N:6][CH:7]=[C:2]2[N:1]=1)[CH3:23]

Participants

3

Reactant 2

HCID 6334PropaneHCID 86717519HCID 86717519, compound

Product 1

HCID 86717524HCID 86717524, compound

Procedure

This compound was prepared according to the procedure of Example 34, steps 12, using {(1R,2S,4S)-4-[(6-aminothieno[3,2-b]pyridin-7-yl)amino]-2-methoxycyclohexyl}acetonitrile (racemic) and propane, 1,1,1-triethoxy- as the starting material. LCMS calculated for C19H23N4OS (M+H)+: m/z=355.2. Found: 355.1.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-24237522da50434d82e6e46da2c1cac5
Source dataset
uspto-grants-2015_11
Patent number
US09181271B2

Reaction notes

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