HRID712223

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C=CCC1(C(=O)OCC)CCN(C(=O)OC(C)(C)C)CC1

HCID16218270

1-tert-Butyl 4-ethyl 4-(prop-2-en-1-yl)piperidine-1,4-dicarboxylate

C16H27NO4

HCID20443148

1,4-Dioxane hydrochloride

C4H9ClO2

PRODUCTS

生成物

HCID53429630

Ethyl 4-(prop-2-en-1-yl)piperidine-4-carboxylate--hydrogen chloride (1/1)

C11H20ClNO2

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

To an ice-cold solution of 1-tert-butyl 4-ethyl 4-allylpiperidine-1,4-dicarboxylate (2 g, 6.70 mmol) in 1,4-dioxane (10 mL) was added HCl-dioxane (4.0 M, 15 mL) solution and the mixture stirred at rt for 30 min. After completion of reaction (by TLC), the solvent was evaporated to obtain a brownish solid material (1.30 g) that was carried forward to the next step without further purification. MS: 198.28 [M+H]+.

WORKUP

后处理

customAfter completion of reaction (by TLC)
customthe solvent was evaporated