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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 712225생성일: 2026년 10월 25일

2-Benzyl-hexahydro-cyclopenta[c]pyrrole-3a-carboxylic acid methyl ester → Methyl octahydrocyclopenta[c]pyrrole-3a-carboxylate

https://huagongshe.com/reaction/712225

반응식

참여 물질

역할이름HCID투입량
반응물2-Benzyl-hexahydro-cyclopenta[c]pyrrole-3a-carboxylic acid methyl esterHCID 4118328—
촉매Palladium hydroxideHCID 9942167—
용매MethanolHCID 887—
생성물Methyl octahydrocyclopenta[c]pyrrole-3a-carboxylateHCID 66977181—

반응 단계

To a stirred solution of methyl 2-benzyloctahydrocyclopenta[c]pyrrole-3a-carboxylate (2.0 g, 7.69 mmol) in MeOH (15.0 mL) was added palladium hydroxide (0.20 g, 10% w/w) and the mixture stirred at rt for 16 h under H2 atmosphere. After completion of reaction (by TLC), the reaction mixture was passed through celite and the solvent evaporated. The crude (1.50 g) residue was carried forward for the next step without further purification. MS: 170.18 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09181234B2
출처 데이터셋uspto-grants-2015_11
ORD IDord-09a6abba829b491280d5efffeeb37fb7
출처 메모uspto-grants-2015_11