Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Benzyl-hexahydro-cyclopenta[c]pyrrole-3a-carboxylic acid methyl ester → Methyl octahydrocyclopenta[c]pyrrole-3a-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Benzyl-hexahydro-cyclopenta[c]pyrrole-3a-carboxylic acid methyl ester | HCID 4118328 | — |
| 촉매 | Palladium hydroxide | HCID 9942167 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl octahydrocyclopenta[c]pyrrole-3a-carboxylate | HCID 66977181 | — |
반응 단계
To a stirred solution of methyl 2-benzyloctahydrocyclopenta[c]pyrrole-3a-carboxylate (2.0 g, 7.69 mmol) in MeOH (15.0 mL) was added palladium hydroxide (0.20 g, 10% w/w) and the mixture stirred at rt for 16 h under H2 atmosphere. After completion of reaction (by TLC), the reaction mixture was passed through celite and the solvent evaporated. The crude (1.50 g) residue was carried forward for the next step without further purification. MS: 170.18 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09181234B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-09a6abba829b491280d5efffeeb37fb7 |
| 출처 메모 | uspto-grants-2015_11 |