HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Indolylboronic acid → US9814704, Example 21
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Indolylboronic acid | HCID 2734361 | — |
| Reactant | 3,4,5-Trimethoxybenzeneboronic acid | HCID 2734390 | — |
| Reactant | 6-(Dimethylamino)pyridine-3-boronic acid | HCID 2763271 | — |
| Reactant | 5-bromo-3-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine | HCID 49759066 | — |
| Reactant | 5-bromo-3-(1H-indol-5-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine | HCID 66779176 | — |
| Product | US9814704, Example 21 | HCID 66778750 | — |
Reaction Steps
Compound X was prepared by a method analogous to that described in Example 1 by substituting 6-(dimethylamino)pyridin-3-ylboronic acid for 1H-indol-5-ylboronic acid in the reaction with Intermediate A and 6-(dimethylamino)pyridin-3-ylboronic acid for 3,4,5-trimethoxyphenylboronic acid in the reaction with Intermediate B. HPLC retention time: 1.17 minutes. MS ESI (m/z): 359.4 (M+H)+, calc. 358.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181247B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-d6909d78f2e846ab92f5832c2244d793 |
| Source note | uspto-grants-2015_11 |