Hydrochloric Acid → HCID 117667525, compound

Participants

Reaction Steps

To the 5-(8-carbamoyl-5,6,7,8-tetrahydro-[1,8]naphthyridin-3-yl)-3′,4′,5′,6′-tetrahydro-2′H-[3,4′]bipyridinyl-1′-carboxylic acid tert-butyl ester (19.3 mg, 0.04 mmol) in 1 mL of CH2Cl2 is added 1 mL of 4 M HCl in dioxane. The mixture is stirred for 16 h. The mixture is concentrated to give 16.5 mg of 6-(1′,2′,3′,4′,5′,6′-hexahydro-[3,4]bipyridinyl-5-yl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid amide

Provenance & Evidence