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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712667Generated: October 30, 2026

HCID 117667312, compound → HCID 117667108, compound

https://huagongshe.com/reaction/712667

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 117667312HCID 117667312—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 117667108HCID 117667108100.5%

Reaction Steps

A stirred suspension of 6-(5-benzyloxy-pyridin-3-yl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid amide (167 mg, 0.46 mmol) in EtOH (10 mL) is hydrogenated over 10% palladium on carbon (17 mg) under balloon pressure for 16 h. The catalyst is removed by filtration through diatomaceous earth, washing well with DCM. The solvent is evaporated to afford the title compound (125 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181272B2
Source datasetuspto-grants-2015_11
ORD IDord-dcbf355a098842118ad34311da439492
Source noteuspto-grants-2015_11