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HRID712766

反应详情

EQUATION

反应方程式

HRID 712766 的结构方程式

REACTANTS

反应物

2
结构：Oc1cncc(Br)c1
HCID599529

3-Bromo-5-hydroxypyridine

C5H4BrNO

结构：CC(C)(C)OC(=O)N1CCCc2cc(B3OC(C)(C)C(C)(C)O3)cnc21
HCID123216343

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCCc2cc(-c3cncc(O)c3)cnc21
HCID117667242

1,1-Dimethylethyl 3,4-dihydro-6-(5-hydroxy-3-pyridinyl)-1,8-naphthyridine-1(2H)-carboxylate

C18H21N3O3

PROCEDURE

实验过程

6-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester is coupled with 5-bromo-pyridin-3-ol to give 6-(5-hydroxy-pyridin-3-yl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester using Suzuki Coupling Method VI.