HCID 117667179, compound → 3-{2-[5-(5,6,7,8-Tetrahydro-[1,8]naphthyridin-3-yl)-pyridin-3-yloxy]-ethyl}-oxazolidin-2-one

Participants

Reaction Steps

6-{5-[2-(2-Oxo-oxazolidin-3-yl)-ethoxy]-pyridin-3-yl}-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester (0.305 mmol) is dissolved in 2 mL of a 20% TFA solution in CH2Cl2 and the solution is shaken overnight at room temperature. The reaction is evaporated to dryness to give crude 3-{2-[5-(5,6,7,8-tetrahydro-[1,8]naphthyridin-3-yl)-pyridin-3-yloxy]-ethyl}-oxazolidin-2-one and used as is in the next step.

Provenance & Evidence