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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712776Generated: October 29, 2026

HCID 117667373, compound → HCID 117667659, compound

https://huagongshe.com/reaction/712776

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 117667373HCID 117667373—
ReactantHCID 123231095HCID 123231095—
ProductHCID 117667659HCID 117667659—

Reaction Steps

6-Bromo-7-cyano-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid amide is coupled with 4-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-3-yl]-tetrahydro-pyran-4-ol (which is prepared according to Step 4 of Example 119) to give the titled product using Suzuki Coupling Method VI.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181272B2
Source datasetuspto-grants-2015_11
ORD IDord-164db7a138964923864a33daab176f78
Source noteuspto-grants-2015_11