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HRID712835

反应详情

EQUATION

反应方程式

HRID 712835 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[Na+].[Na+]
HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

结构：FC(F)(F)c1cccc(CBr)c1
HCID123061

1-(Bromomethyl)-3-(trifluoromethyl)benzene

C8H6BrF3

结构：O=C(O)[C@H]1C[C@@H](O)CN1
HCID440014

cis-4-Hydroxy-D-proline

C5H9NO3

PRODUCTS

生成物

1
结构：O=C(OCc1cccc(C(F)(F)F)c1)C1CC(O)CN1Cc1cccc(C(F)(F)F)c1
HCID90353857

未命名化合物

PROCEDURE

实验过程

The title compound (D81) (1.02 g) was prepared according to the general procedure for substituted benzyl amines preparation starting from cis-4-Hydroxy-D-proline (4.0 g; available from Aldrich#H5877) and 3-(Trifluoromethyl)benzyl bromide (9.37 ml). (Na2CO3: 2.5 eq; Reaction time: 24 hrs; 60° C.).