Ethanol → HCID 71186559, compound

Participants

Reaction Steps

To a solution of methyl 4-((1S)-1-(1-benzylazetidine-2-carboxamido)ethyl)benzoate (D76) (98 mg, 0.278 mmol in EtOH (20 ml) Pd/C 10% (90 mg, 0.083 mmol) and ammonium formate (52 mg, 0.83 mmol) were added and the heterogeneous solution was left stirring at RT for 20 hrs. Further addition of Pd/C 10% (90 mg, 0.083 mmol) and ammonium formate (52 mg, 0.83 mmol) was done and the resulting mixture was stirred at RT for 5 hrs. Catalyst was filtered off and the solvent evaporated to afford the title compound (D109) (60 mg).

Provenance & Evidence